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The second remarkable site, known as the Z-site, identified by the screening, is located within the large trypanothione cavity but corresponds to a region not yet exploited for inhibition

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doi: 10.1152/ajprenal.00183.2002

Research teams at institutions studying metabolic disease have documented this combination in pilot studies, noting that the stack produces a more favorable shift in body composition markers (lean mass retention, visceral fat reduction) than either compound used alone